Citric acid-d4-1 is a deuterated labeled version of Citric acid that acts as a natural preservative and food tartness enhancer. It has been observed to induce apoptosis and cell cycle arrest in HaCaT cells and can lead to oxidative damage of the liver by reducing antioxidative enzyme activities. This compound is also widely used across various industries as an acidulant, emulsifier, sequestrant, and buffering agent.
- Deuterated labeled compound
- Can be used as a tracer
- Can be used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS
- Stable heavy isotopes incorporated into drug molecules for quantitation during drug development
- Deuteration has potential to affect the pharmacokinetic and metabolic profiles of drugs